Pierwotny śródczaszkowy bazaloidalny rak płaskonabłonkowy

Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to date. We herein describe a case of primary intracranial squamous cell carcinoma arising de novo in the right frontal lobe in a 35-year-old woman treated with a combination of surgery and postoperative conformal radiation. We have also shed light on the biology and the therapeutic options of this enigmatic tumour.Pierwotny śródczaszkowy rak płaskonabłonkowy jest wyjątkową rzadkością i w większości przypadków rozwija się w wyniku zezłośliwienia zmian o charakterze dysembriogenetycznym, np. torbieli naskórkowej lub skórzastej. Śródczaszkowy rak płaskonabłonkowy powstały de novo jest jeszcze rzadszy – dotąd opisano 4 takie przypadki. W niniejszej pracy przedstawiono przypadek nowotworu powstałego de novo w prawym płacie czołowym u 35-letniej chorej, którą z tego powodu poddano leczeniu chirurgicznemu i pooperacyjnej radioterapii konformalnej. Podano również informacje na temat biologii i możliwości leczenia tego zagadkowego guza

Adult Opisthorchis viverrini Flukes in Humans, Takeo, Cambodia

(1). Sophisticated laboratory methods, although sensitive, are costly. The immunochromatographic strip test that uses recombinant K39 antigen (rK39), although satisfactory in India, is less sensitive in Africa, Latin America, and Mediterranean regions (2). Post–kala-azar dermal leishmaniasis (PKDL), a sequel to VL in India and Africa, is often confused with other skin diseases (3,4). Diagnosis of VL in dogs in Latin America and Mediterranean countries remains confusing because of rampant asymptomatic infections and elevated antibodies against Leishmania spp. (5)

Comparison of Remifentanil and Fentanyl for Postoperative Pain Control after Abdominal Hysterectomy

Purpose: In this randomized, double-blind study, we investigated the analgesic efficacy and side effects of continuous constant-dose infusions of remifentanil after total abdominal hysterectomy and compared it to fentanyl. Materials and Methods: Fifty-six adult female patients scheduled for elective total abdominal hysterectomy were enrolled in this study. Patients were randomly assigned to two groups according to fentanyl (group F, n = 28) or remifentanil (group R, n = 28) for postoperative analgesia. Patients in group F were given fentanyl intravenously with an infusion rate of fentanyl 0.5 μg/kg/hr; group R was given remifentanil with an infusion rate of remifentanil 0.05 μg/kg/ min for 2 days. Pain intensity at rest, occurrence of postoperative nausea and vomiting (PONV), dizziness, pruritus, and respiratory depression were assessed 1 hr after arrival at the post-anesthesia care unit, at 6; 12; 24; and 48 hr postoperation and 6 hr post-infusion of the study drug. Pain was evaluated by using visual analogue scale (VAS; 0- 10). The time that patients first requested analgesics was recorded as well as additional analgesics and antiemetics. Results: There were no significant differences in VAS, time to first postoperative analgesics, and additional analgesics between the 2 groups. The incidences and severities of PONV and opioid related side effects were not different between the groups; however, there were 3 episodes (10.7%) of serious respiratory depression in group R. Conclusion: Continuous infusion technique of remifentanil did not reveal any benefits compared to fentanyl. Furthermore, it is not safe for postoperative analgesia in the general ward

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

Contributions of Selected Indian Researchers to Multi-Attribute Decision Making in Neutrosophic Environment: An Overview

The objective of the study is to present a brief review of the pioneering contributions of personalities as diverse as those of P. P. Dey, K. Mondal, P. Biswas, D. Banerjee, S. Dalapati, P. K. Maji, A. Mukherjee, T. K. Roy, B. C. Giri, H. Garg, S. Bhattacharya. A survey of various concepts, issues, etc. related to neutrosophic decision making is discussed. New research direction of neutrosophic decision making is also provided

Contributions of Selected Indian Researchers to Multi Attribute Decision Making in Neutrosophic Environment: An Overview

Multi-attribute decision making (MADM) is a mathematical tool to solve decision problems involving conflicting attributes. With the increasing complexity, uncertainty of objective things and the neutrosophic nature of human thought, more and more attention has been paid to the investigation on multi attribute decision making in neutrosophic environment, and convincing research results have been reported in the literature

Effective role of vibrational annealing in enhancing room temperature physical properties of Co doped ZnO nanoparticles by using novel TVA technique

Well-annealed nanocrystalline semiconductor materials in pellet or thin film form, composed of small grains with a high surface-to-volume ratio, are considered as promising candidates for multiple device applications. However, no such method is available yet that can control the grain size of such samples during heat treatment. In this present work, a novel thermo-vibrational annealing (TVA) setup for processing nanocrystalline materials was designed and fabricated in-house. Here both thermal and mechanical vibrational energy were simultaneously applied to the sample during annealing, followed by vibrational dry quenching in the presence of an inert gas environment. Co-doped ZnO pellets were synthesized by chemical route pyrophoric method followed by annealing at 800 °C for 4 h using this set up. For comparison, one pellet was annealed with vibration with calibrated vibration at a speed of 360 rpm, and another pellet was annealed without vibration. X-ray diffraction (XRD), Raman and Fourier transform Infrared (FTIR) spectroscopic studies showed the formation of a single crystalline phase with hexagonal wurtzite structure of both the samples and the proper incorporation of Co2+ ions into the ZnO matrix without any impurity phases, which was also confirmed by energy dispersive X-ray (EDX) spectroscopy studies. Scanning electron microscopy (SEM) and high-resolution transmission electron microscopy (HRTEM) studies confirmed the decrease in average grain and particle size of the sample when processed with the TVA setup. Ultraviolet–Visible spectra showed that the bandgap energy of the Co-doped ZnO sample varies inversely with particle size. Hall-effect measurements demonstrated the semiconducting nature of both samples with n-type charge carriers. The presence of Co2+ ions in the wurtzite ZnO lattice was confirmed by X-ray photoelectron spectroscopy (XPS). The magnetic properties were studied using a SQUID magnetometer, which confirmed that a Co doped ZnO sample annealed with the TVA technique exhibit better room temperature ferromagnetism properties compared to sample annealed without vibration. Based on these studies, it was believed that the sample annealed by mechanical vibrational energy with vibrational dry quenching has a great influence on several physical properties of any material and hence Co doped ZnO sample processed with this TVA technique can be used as a promising candidate for multiple sensor and magnetic storage devices

Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing

Mycobacterium marinum is the causative agent for the tuberculosis-like disease mycobacteriosis in fish and skin lesions in humans. Ubiquitous in its geographical distribution, M. marinum is known to occupy diverse fish as hosts. However, information about its genomic diversity is limited. Here, we provide the genome sequences for 15 M. marinum strains isolated from infected humans and fish. Comparative genomic analysis of these and four available genomes of the M. marinum strains M, E11, MB2 and Europe reveal high genomic diversity among the strains, leading to the conclusion that M. marinum should be divided into two different clusters, the "M"- and the "Aronson"-type. We suggest that these two clusters should be considered to represent two M. marinum subspecies. Our data also show that the M. marinum pan-genome for both groups is open and expanding and we provide data showing high number of mutational hotspots in M. marinum relative to other mycobacteria such as Mycobacterium tuberculosis. This high genomic diversity might be related to the ability of M. marinum to occupy different ecological niches